The Inlabtec TA12 Serial Diluter was developed in response to the demand from food culture and probiotic producers undertaking final quality control with the standard plate count method. Because you are placing the sample into a sterile, empty Serial Dilution Bag instead of a prefilled test tube, then adding the diluent at the touch of a button, performing serial dilutions with the TA12 is fast, reliable, and much less taxing than traditional procedures. The TA12 combines two lines of six dilution bags in parallel, and the telescopic dispensing arm makes changing between the two rows of bags easy and convenient. Any kind of diluent can be used, enabling probiotic producers to use preferred diluents such as skimmed milk, for which prefilled test tubes are not available. Serial Dilution Bags are made from high-purity polyethylene, guaranteed to be free of any substances that could inhibit proliferation of sensitive cells.

AMS Biotechnology offers an extensive portfolio of Poly (ADP-ribose) polymerase (PARP) isozymes such as assay kits, inhibitors, recombinant histone substrates, and screening/profiling services for over 10 different PARPs. PARPs play key signaling roles in apoptosis, DNA excision and repair, and chromatin structure. They are also involved in transcriptional regulation of several signaling pathways, including genes involved in inflammation. The latest addition to the range is the PARPtrap Assay Kit, which is designed to measure PARP1/DNA complex formation in a high-throughput screening assay using fluorescence polarization. The kit comes in a convenient 96-well format, supplied with purified PARP1 enzyme, fluorescent-labeled nicked DNA, and PARPtrap assay buffer for 100 enzyme reactions. Without the PAR reaction, PARP1 binds to the fluorescent-labeled nicked DNA, resulting in the emission of highly polarized light. However, after autoribosylation of PARP1, the nicked DNA is dissociated from PARP1 and rotates freely, emitting less polarized light.

With the Andor Dragonfly, you can image with an unrivaled combination of speed, sensitivity, confocality, and resolution beyond the diffraction limit. It is now available in the compact 200 series and the full-model 500 series. Dragonfly naturally benefits from Andor EMCCD and sCMOS technologies, and with its motorized optical zoom, the system delivers industry-leading signal-to-noise and image fidelity. Applications range from single-molecule to live-cell confocal, and from total internal reflection fluorescence microscopy (TIRFM) to whole-embryo and thick-tissue imaging, and all benefit from the system's speed and sensitivity. Dragonfly delivers real-time visualization for rapid specimen evaluation and ClearView-GPU (graphics processing unit) deconvolution to maximize resolution and throughput.



Micro-Flow Imaging (MFI) combines the direct-imaging capabilities of digital microscopy with the precise control of microfluidics. What does that get you? High-resolution images with 85% sampling efficiency, more precise counts and sizing with full morphological detail for all subvisible particles in your sample, and the complete confidence that you can accurately identify every possible particle type—from protein aggregates to air bubbles. Images of the sample are captured as it passes through the flow cell's sensing zone. Every particle in every image is then analyzed to create a database of particle count, size, transparency, and morphology (or shape). And you'll have visual verification on the spot, as images are displayed in real time. You can also display results for many samples at once, making it easy to monitor stability and comparability. If you're looking for broader, deeper analysis of your biotherapeutic products, MFI is the particle analysis tool for you.

The SP8 FALCON (FAst Lifetime CONtrast) from Leica Microsystems can record lifetime contrast 10x faster than previous solutions. This lifetime information lets researchers monitor interactions between proteins in living cells as well as providing extra contrast to clearly separate a multitude of fluorophores. The FALCON offers lifetime imaging with fluorescence lifetime imaging (FLIM) in an instant. Detecting molecular interactions with biosensors using fluorescence resonance energy transfer (FRET) is as easy as recording standard confocal data. Even complex experiments are easy to perform, opening a wide range of applications. As the FALCON is part of the SP8 family, lifetime imaging can be easily combined with other modalities. For example, combine FLIM with the SP8 DIVE for deep imaging, the SP8 STED for nanoscopy resolution, or the LAS X Navigator software module for mosaic tiling, which ensures you always have a clear roadmap to brilliant data. 

Our Good Liquid Handling (GLH) Kits provide users with everything necessary to verify and calibrate their systems to industry standards. They furnish reliable instrument services, products, and training, and are medically manufactured to ensure quality and performance. GLH Kits deliver liquid classes, methods, and recommendations for automated pipetting for any scenario. With three different kits available, you will surely find something to meet your needs. A unique feature included in the kits is Good Liquid Handling's integrated software, GLH Tracker, which allows results to be uploaded to a cloud-based resource accessible to additional team members as well as the Good Liquid Handling experts, who can offer troubleshooting or consultations. The tracker lets users drag and drop through a WebDAV (Web Distributed Authoring and Versioning) collaboration platform (BiotechCloud.org), to share methods and exchange data for processing or sharing through one's optional LinkedIn account. Kits support a wide range of volumetric measurements and are compatible with 96- or 384-well plates.  

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Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.

12x75 test tube

A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.

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